Alcohols and polyols
- (1)
- (55)
- (350)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (155)
- (1)
- (63)
- (29)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (10)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (5)
- (5)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (81)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (9)
- (6)
- (8)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (86)
- (1)
- (5)
- (72)
- (3)
- (5)
- (238)
- (4)
- (2)
- (2)
- (21)
- (281)
- (17)
- (1)
- (6)
- (279)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (731)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
- (3)
- (3)
- (4)
- (11)
- (3)
- (2)
- (1)
- (3)
- (2)
- (3)
- (2)
- (3)
- (1)
- (3)
- (6)
- (3)
- (2)
- (2)
- (2)
- (3)
- (7)
- (7)
- (1)
- (3)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (3)
- (3)
- (1)
- (4)
- (3)
- (3)
- (6)
- (5)
- (6)
- (7)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (3)
- (4)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (9)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (7)
- (2)
- (3)
- (2)
- (2)
- (6)
- (2)
- (4)
- (1)
- (11)
- (2)
- (2)
- (4)
- (6)
- (2)
- (4)
- (1)
- (1)
- (4)
- (8)
- (2)
- (3)
- (2)
- (12)
- (6)
- (2)
- (2)
- (14)
- (2)
- (3)
- (1)
- (2)
- (11)
- (1)
- (8)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (2)
- (12)
- (2)
- (2)
- (3)
- (4)
- (9)
- (3)
- (6)
- (3)
- (5)
- (2)
- (7)
- (2)
- (3)
- (12)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (2)
- (11)
- (1)
- (3)
- (4)
- (1)
- (6)
- (4)
- (2)
- (4)
- (1)
- (2)
- (5)
- (2)
- (2)
- (6)
- (2)
- (2)
- (3)
- (2)
- (2)
- (7)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
- (5)
- (3)
- (6)
- (3)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (2)
- (5)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (2)
- (2)
- (3)
- (3)
- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (6)
- (3)
- (4)
- (3)
- (1)
- (4)
- (2)
- (3)
- (2)
- (7)
- (4)
- (4)
- (3)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (1)
- (2)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (8)
- (2)
- (5)
- (4)
- (1)
- (2)
- (2)
- (1)
- (4)
- (8)
- (3)
- (5)
- (2)
- (6)
- (4)
- (2)
- (2)
- (5)
- (6)
- (2)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (1)
- (2)
- (3)
- (4)
- (1)
- (7)
- (1)
- (1)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (3)
- (5)
- (4)
- (4)
- (1)
- (3)
- (2)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (2)
- (4)
- (3)
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- (3)
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Filtered Search Results
Medchemexpress LLC VU0453379 hydrochloride | 00-00-0 | MFCD28987471 | 99.0% | 471.03 g·mol⁻¹ | C26H35ClN4O2 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VU0453379 hydrochloride is a selective, CNS-penetrant positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R) used as a research reagent to study GLP-1R pharmacology. It potentiates GLP-1R signaling with an EC50 of approximately 1.3 μM and is supplied as a high-purity hydrochloride salt for in vitro and in vivo studies.
- Selective GLP-1R positive allosteric modulator with EC50 ~1.3 μM.
- CNS-penetrant compound suitable for central nervous system studies.
- High purity (listed as 99.0%) for reproducible research results.
- Provided as hydrochloride salt with molecular weight 471.03 g·mol⁻¹.
- Available in small research pack sizes and DMSO solutions for assay use.
- Store at 4°C, protected from moisture.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Leonurine hydrochloride | 24735-18-0 | 347.79 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Leonurine hydrochloride | 24735-18-0 | 347.79 | 50 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | 99.5% | 458.08 | C27H40ClN3O | 10 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Nevanimibe hydrochloride is the hydrochloride salt of Nevanimibe, an orally active, selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) with demonstrated activity in preclinical studies. It is provided for research use in solid and solution forms and has been characterized for potency and basic physicochemical properties.
- Selective ACAT1 inhibitor with low-nanomolar potency
- Demonstrated activity against ACAT2 in cellular assays
- Induces apoptosis in cell models relevant to adrenocortical tissues
- Chemical formula C27H40ClN3O and molecular weight 458.08
- Available as solid and DMSO solution formats for research use
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 10 G
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Trazodone hydrochloride (AF-1161) is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). It has antidepressant and anti-insomnious activity and exerts antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.
- Serotonin receptor antagonist and reuptake inhibitor
- Exhibits antidepressant and anti-insomnious activity
- Antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors
- Minimal anticholinergic effects
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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | MFCD01698392 | 99.0% | C22H31ClN2 | 100 MG
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Aprindine hydrochloride is an Ib-class anti-arrhythmic agent primarily used in the study of atrial fibrillation and ventricular arrhythmias. It functions by stabilizing cardiac electrical activity through multiple mechanisms.
- Blocks sodium channels to reduce excitability and conduction velocity of cardiac muscle cells.
- Inhibits delayed potassium currents, prolonging the atrial effective refractory period.
- Inhibits atrial fibrillation.
- Regulates intracellular calcium ion concentration by inhibiting the Na+/Ca2+ exchange current.
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Medchemexpress LLC Terazosin hydrochloride | 63074-08-8 | 99.9% | 50 MG
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Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and opening the bladder. It has potential for the treatment of benign prostatic hyperplasia (BPH) and high blood pressure.
- Relaxes blood vessels
- Opens the bladder
- Potential for treatment of benign prostatic hyperplasia (BPH)
- Potential for treatment of high blood pressure
- For research use only
- Solid appearance
- White to off-white color
- Purity: 99.9%
- Molecular weight: 423.89
- Molecular formula: C19H26ClN5O4
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Medchemexpress LLC Betaxolol hydrochloride | 63659-19-8 | 98.1% | 5 MG
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Betaxolol hydrochloride is a selective beta1 adrenergic receptor blocker, useful for research into hypertension and glaucoma. It acts as a cardioselective beta-adrenergic receptor blocking agent, potentially safer for patients with reactive airway disease due to reduced systemic beta 2- and beta 1-adrenergic receptor blockade compared to other agents. In vivo studies show it can attenuate anxiety-like behavior during early withdrawal from chronic cocaine administration in rats.
- Selective beta1 adrenergic receptor blocker
- Used for research of hypertension and glaucoma
- Cardioselective beta-adrenergic receptor blocking agent
- Attenuates anxiety-like behavior during cocaine withdrawal in rats
- Potentially safer for patients with reactive airway disease
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Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | 98.1% | 457.91 | 1 ML
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Topotecan hydrochloride is a Topoisomerase I inhibitor with potent antineoplastic activities, intended for research use only.
- Inhibits Topoisomerase I
- Displays potent antineoplastic activities
- Inhibits proliferation of human glioma cells and glioma stem cells
- Induces cell cycle arrest in G0/G1 and S phases
- Promotes apoptosis
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Medchemexpress LLC 2-Pyridinecarboxylic acid, 3-mercapto-, hydrochloride (1:1) | 320386-54-7 | 96.4% | 25 MG
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SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It functions as a potent hypoglycemic agent by inhibiting glucose synthesis, and also inhibits Asn metabolism, leading to an increase in amino acids and amides.
- Orally active PEPCK inhibitor (Ki: 2-9 μM)
- Potent hypoglycemic agent
- Inhibits glucose synthesis
- Inhibits Asn metabolism
- Increases amino acids and amides
- Inhibits C2C12 cell proliferation in vitro
- Induces myogenic differentiation of C2C12 cells
- Reduces mRNA expression of Pck2 and genes associated with serine biosynthesis
- Reduces blood glucose in starved rats in vivo
- Neutralizes Salbutamol-mediated hyperglycemia in rabbits
- Reduces Pyruvate-induced blood glucose level in rats
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Medchemexpress LLC Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino] butyl ester, hydrochloride | 24735-18-0 | 347.79 | 1 ML
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Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino] butyl ester, hydrochloride | 24735-18-0 | 347.79 | 1 ML
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Medchemexpress LLC Imeglimin hydrochloride | 775351-61-6 | MFCD28167741 | 100.0% | 191.66 g/mol | C6H14ClN5 | 10 MG
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Imeglimin hydrochloride is the hydrochloride salt of imeglimin, an oral glucose-lowering small molecule that modulates mitochondrial metabolism and improves insulin sensitivity. It is supplied as a research-grade reagent for in vitro and in vivo studies of glucose homeostasis and mitochondrial function.
- High purity suitable for research applications.
- Molecular weight 191.66 g/mol and chemical formula C6H14ClN5.
- Provided as a solid in a 10 MG pack.
- Used to study insulin sensitivity and mitochondrial metabolism.
- Includes a product datasheet with analytical information.
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Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.27% | 274.79 | 25 MG
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PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.
- Binds to the surface cavity and stabilizes Y220C (a p53 mutant)
- Kd of 167 μM (p53-Y220C)
- Relative binding affinity (Kd) of 150 μM in Ln229 cells
- Slows down its thermal denaturation rate
- Reduces the cell viability of engineered variants of Ln229 cells (125 μM, 48 hours)
- Enhances pro-apoptotic activity in all variants of Ln229 cells (p53wt, p53Y220C, p53G245S, p53R282W) when combined with NSC 123127 (1 μM)
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Medchemexpress LLC Asenapine hydrochloride | 1412458-61-7 | 99.95% | 322.23 | 100 MG
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Asenapine hydrochloride is an atypical antipsychotic that acts as an antagonist of serotonin, adreno, dopamine, and histamine receptors. It is utilized in research for schizophrenia and bipolar disorder.
- Acts as an antagonist of serotonin receptors (pKi: 8.4-10.5).
- Acts as an antagonist of adrenoceptors (pKi: 8.9-9.5).
- Acts as an antagonist of dopamine receptors (pKi: 8.9-9.4).
- Acts as an antagonist of histamine receptors (pKi: 8.2-9.0).
- Purity of 99.95%.
- Soluble in H2O (100 mg/mL) and DMSO (50 mg/mL).
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | 99.8% | 1 ML
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Amiloride hydrochloride is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). It also acts as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is suitable for research applications targeting these pathways.
- Inhibitor of epithelial sodium channel (ENaC)
- Inhibitor of urokinase-type plasminogen activator receptor (uTPA)
- Blocker of polycystin-2 (PC2; TRPP2) channel
- Relatively selective ENaC inhibitor with IC50 ranging from 0.1 to 0.5 μM
- Demonstrated to reverse initial increases in collagen deposition in DOCA-salt hypertensive rats
- Delays the onset of proteinuria in stroke-prone spontaneously hypertensive rats (SHRSP)
- Antagonizes or prevents aldosterone actions in animal models of salt-dependent hypertension
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Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 100 MG
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SB-408124 Hydrochloride is a selective, non-peptide orexin receptor 1 (OX1) antagonist. It demonstrates high potency with Ki values of 57 nM in whole cells and 27 nM in membranes, exhibiting 50-fold selectivity over the OX2 receptor. This compound is for research use only.
- Potent OX1 receptor antagonist (Ki: 57 nM in whole cells, 27 nM in membranes)
- Exhibits 50-fold selectivity over OX2 receptor
- Attenuates orexin A-induced AVP mRNA levels in neuronal cultures
- Reduces anxiety and restores corticoliberin levels in vivo
- Demonstrates an anxiolytic effect
- Reduces mean arterial pressure in salt-sensitive rats
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