Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,501 – 4,515 of 5,341 results

4,501

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 1 ML

Octodrine hydrochloride is a central nervous activator that functions by increasing the uptake of dopamine and noradrenaline. It has been observed to increase pain threshold, cardiac rate, and myocardial contractility.

Increases dopamine and noradrenaline uptake
Increases pain threshold
Positive chronotropic effect on cardiac rate
Positive inotropic effect on myocardial contractility
For research use only

Pricing & Availability

4,502

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 500 MG

Octodrine hydrochloride is a central nervous activator that increases the uptake of dopamine and noradrenaline. It increases the pain threshold, cardiac rate, and myocardial contractility. This product is for research use only.

Increases uptake of dopamine and noradrenaline
Increases pain threshold
Increases cardiac rate
Increases myocardial contractility

Pricing & Availability

4,503

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML

AMXI-5001 hydrochloride is a potent, orally active, and dual PARP1/2 and microtubule polymerization inhibitor. It shows selective antitumor cytotoxicity across a wide range of human cancer cells with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors, and can induce complete regression of established tumors, including very large ones.

Potent and orally active
Dual PARP1/2 and microtubule polymerization inhibitor
Selective antitumor cytotoxicity across a wide range of human cancer cells
Significantly lower IC50s compared to existing clinical PARP1/2 inhibitors
Induces complete regression of established tumors

Pricing & Availability

4,504

Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML

DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF) with an IC50 of 698 nM. It significantly inhibits leukemia cell proliferation in human leukemia MV-4-11 cells (EC50 120 nM, IC50 0.89 μM). The compound decreases downstream oncogene expression and c-Myc protein levels, with minimal effects on normal cells. Intended for research use only.

Inhibits bromodomain PHD finger transcription factor (BPTF)
IC50 of 698 nM against BPTF
Inhibits leukemia cell proliferation
Decreases oncogene expression and c-Myc protein
Minimal effects on normal cells
Off-white to light yellow solid appearance
Molecular weight: 433.95
Chemical formula: C20H24ClN5O2S

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4,505

Medchemexpress LLC SB 271046 Hydrochloride | 209481-24-3 | 99.9% | C20H23Cl2N3O3S2 | 50 MG

SB 271046 Hydrochloride is a potent, selective, orally active, and BBB-permeable 5-HT6 receptor antagonist. It exhibits high selectivity for the 5-HT6 receptor compared to 55 other receptors, binding sites, and ion channels, and also demonstrates anticonvulsant activity.

Potent, selective, orally active, and BBB-permeable 5-HT6 receptor antagonist
Over 200-fold selectivity for the 5-HT6 receptor
Shows anticonvulsant activity (EC50=0.16 μM)
Antagonizes 5-HT-induced stimulation of adenylyl cyclase activity (pA2=8.71)
Increases seizure threshold in rat maximal electroshock seizure threshold (MEST) test in vivo

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4,506

Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 g/mol | C21H25ClN2O4 | 10MM 1ML

Carmoterol hydrochloride is a potent, selective, long-acting β2-adrenoceptor agonist supplied for research use. It is available as solid samples and as a ready-to-use 10 mM solution in DMSO (1 mL), and is intended for pharmacology and respiratory research including bronchodilation, asthma, and COPD models.

High purity suitable for research use.
Available as solid and as a 10 mM solution in DMSO.
Molecular weight 404.89 g/mol.
CAS number 137888-11-0 for unambiguous identification.
Supplied as the hydrochloride salt for improved solubility.
Suitable for β2-adrenergic receptor pharmacology studies.

Pricing & Availability

4,507

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML

Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. It prevents the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G by exerting a proximal effect in the complement cascade reaction. It can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Effective and orally-active highly selective factor B inhibitor
IC50 value of 10 nM and KD of 7.9 nM
Prevents destruction (hemolysis) of red blood cells in PNH
Prevents damage of renal cells in IgAN and C3G
Used for the study of complement-mediated diseases
Particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)

Pricing & Availability

4,508

Medchemexpress LLC PF-562271 (hydrochloride) | 939791-41-0 | 98.10% | 543.95 | 5 MG

PF-562271 hydrochloride is a potent, ATP-competitive, and reversible inhibitor targeting FAK (Focal Adhesion Kinase) and Pyk2 (Proline-rich tyrosine kinase 2) kinases, with IC50 values of 1.5 nM and 13 nM, respectively.

Potent, ATP-competitive, and reversible kinase inhibitor.
Selectively targets FAK and Pyk2 kinases.
Exhibits IC50s of 1.5 nM for FAK and 13 nM for Pyk2.
Also inhibits CDK2/E, CDK5/p35, CDK1/B, and CDK3/E.
Impairs cell viability in various cell lines, including Ewing sarcoma.
Inhibits FAK phosphorylation in vivo in a dose-dependent manner.
Demonstrates positive effects on bone tumors, including decreased tumor growth and deposition of new bone.

Pricing & Availability

4,509

Medchemexpress LLC Fingolimod hydrochloride | 162359-56-0 | 99.9% | 1 ML

Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) receptor modulator supplied as a 10 mM solution in DMSO for research use, suitable for cellular and pharmacology studies of S1P signaling.

10 mM solution in DMSO, 1 mL vial.
High purity (99.94%).
Molecular weight 343.93 g/mol.
CAS number 162359-56-0.
Store in solvent at -80°C (up to 6 months) or -20°C (up to 1 month); solid at 4°C.

Pricing & Availability

4,510

Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | 99.9% | 390.93 | 50 MG

Sultopride hydrochloride is a selective antagonist of the dopamine D2 receptor. It has shown increased levels of DOPAC and HVA in the striatum, nucleus accumbens, and medial prefrontal cortex in treated rats.

Acts as a selective antagonist of dopamine D2 receptor.
Demonstrates high purity of 99.92%.
Soluble in water and DMSO for in vitro applications.
Suitable for in vivo studies with protocol for PBS solubility.
Available in solid form, white to off-white in appearance.
Stored at 4°C, sealed, away from moisture.

Pricing & Availability

4,511

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG

Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker that inhibits H+, K+- ATPase through reversible potassium-competitive ionic binding without requiring acid activation. It is being developed as a potential alternative to proton pump inhibitors for treating acid-related diseases.

Potassium-competitive acid blocker.
Inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding.
Does not require acid activation for its inhibitory mechanism.
Developed as a potential alternative for proton pump inhibitors.
Inhibits acid secretion in a dose-dependent manner in in vivo studies.
Efficacy is equal to or greater than that of vonoprazan in various in vivo studies.

Pricing & Availability

4,512

Medchemexpress LLC Sevelamer hydrochloride | 152751-57-0 | 98.0% | 186.08 (monomer) | 5 G

Sevelamer hydrochloride is an orally active phosphate binding agent primarily used for research related to hyperphosphatemia in chronic kidney disease. This compound consists of polyallylamine crosslinked with epichlorohydrin, and is intended for research use only, not for patient treatment.

Orally active phosphate binding agent
Used for research of hyperphosphatemia with chronic kidney disease
Composed of polyallylamine crosslinked with epichlorohydrin
Decreases serum levels of gut-derived uremic toxins (such as IAA) in vitro
Reduces serum phosphate levels in Npt2b-deficient mice in vivo
Leads to a significant decrease in osteoclast number in uremic WT mice
Store at 4°C sealed, away from moisture for solid form

Pricing & Availability

4,513

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 5 G

Octodrine (2-Amino-6-methylheptane) is a central nervous activator that increases the uptake of dopamine and noradrenaline. It is found to increase the pain threshold, cardiac rate (positive chronotropic effect), and myocardial contractility (positive inotropic effect).

Increases the uptake of dopamine and noradrenaline
Increases pain threshold
Increases cardiac rate (positive chronotropic effect)
Increases myocardial contractility (positive inotropic effect)
Functions as a central nervous activator

Pricing & Availability

4,514

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML

Ninhydrin is a chromogenic analytical probe utilized for the quantification of amino acids and proteins. It is widely employed in amino acid analysis of proteins, where most amino acids, excluding proline, undergo hydrolysis and react with ninhydrin, allowing for their colorimetric quantification following chromatographic separation. Ninhydrin interacts with primary and secondary amines to yield a distinctive blue or purple reaction product, diketohydrindylidene-diketohydrindamine.

Functions as a chromogenic analytical probe.
Enables quantification of amino acids.
Facilitates quantification of proteins.
Reacts with most amino acids (excluding proline).
Permits colorimetric quantification post-chromatographic separation.
Interacts with primary and secondary amines.
Generates a blue or purple reaction product.

Pricing & Availability

4,515

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.

Inhibits human TXNIP promoter activity and reduces TXNIP mRNA and protein levels in INS-1 cells.
Lowers glucagon secretion in TC1-6 cells and decreases glucagon secretion and action in vivo.
Reduces glucagon-induced glucose output from primary hepatocytes and blocks hepatic glucose output in vivo.
Reverses obesity- and Streptozotocin (STZ)-induced diabetes and hepatic steatosis in mice.
Orally bioavailable.
Well-tolerated in male C57BL/6J mice.

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Alcohols and polyols

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Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB 271046 Hydrochloride | 209481-24-3 | 99.9% | C20H23Cl2N3O3S2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 g/mol | C21H25ClN2O4 | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PF-562271 (hydrochloride) | 939791-41-0 | 98.10% | 543.95 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fingolimod hydrochloride | 162359-56-0 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | 99.9% | 390.93 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sevelamer hydrochloride | 152751-57-0 | 98.0% | 186.08 (monomer) | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.99% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More